Industry News

News and information on research / medical trials on development of the Male Birth Control Pill

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Revolution Contraceptives receives $200K grant from MCI for Vasalgel™ development 

 Jan 24, 2018 (SAN FRANCISCO) Revolution Contraceptives has received a $200,000 grant from the Male Contraceptive Initiative (MCI), a private non-profit foundation in Raleigh, North Carolina, to support a preclinical formula screening and reversibility study of Vasalgel, its vas-occlusive contraception product. 


  A new option to prevent unwanted pregnancy may soon be on the market 

 Developed by the National Institutes for Health, DMAU is proposed to give another option for couples to help prevent unwanted pregnancy.   Another significant advantage of the DMAU pill versus others put forward prior is that it would only require one dosage a day instead of two or more. 


Male Birth Control Pill Developed, Almost Ready for Use

Male birth control pill has passed all the safety tests and it ready for use. This pill comes in form of a capsule that can be used to suppress male reproductive hormones, making it an appropriate male contraceptive. The pill has been tested for quite some time and scientists have concluded that it works effectively without hitches. 83 men were involved in the testing and it was found that the new prototype pill has not troubling symptoms or side effects.The new pill known as dimethandrolone undecanoate or DMAU has indeed helped in reducing the levels of hormones like testosterone that are required in sperm production.

 Birth Control For Men: What We Know So Far

Birth control for men may be on the horizon due to a study being conducted by the National Institutes of Health (NIH).The study, reported by Bloomberg in November, involves 420 couples and will use a gel treatment that will be applied to the back and shoulders of a male. Here, two types of hormones are used to stop the production of sperm while also maximizing the energy and libido of testosterone.


Top five discoveries in 2018 that can solve unmet medical needs

Male birth control pill shows promising results. For years there hasn't been much progress beyond condom when it came to tackle birth control. In March, researchers at University of Washington, Seattle, announced success in a trial for male birth control pills.


 A new birth-control gel that men rub on their shoulders once a day is being tested in the US 11/29/18

 The couples are the first two of about 420 around the world who will eventually participate in a groundbreaking study of a form of male birth control that gets rubbed into a man's shoulders once a day.

The gel works by inhibiting a man's natural testosterone production. Using a combination of progestin (Nestorone) and testosterone, the treatment interrupts the normal hormone-production processes in the testicles, thereby preventing men from producing viable, mature sperm.

 Gel formulation of a new male contraceptive on trial

 United States government scientists will test an experimental birth control method for men, which would be a major advance in contraception and bring more equality to a family planning burden borne largely by women. It is at present approved by the United States Food and Drugs Administration (US FDA) as a hormonal contraceptive as well as used in treatment of endometriosis in women. 

DMAU (dimethandrolone undecanoate )

 Early Study of Male Birth Control Pill Finds it's Safe and Effective. A new study found a once-daily pill was effective in lowering hormones required for sperm production. ... The new pill, known as DMAU for its chemical name, dimethandrolone undecanoate, is similar to the female birth control pill


RISUG (Reversible inhibition of sperm under guidance) 

 Reversible inhibition of sperm under guidance (RISUG), formerly referred to as the synthetic polymer styrene maleic anhydride (SMA), is the development name of a male contraceptive injection developed at IIT Kharagpur in India by the team of Dr. Sujoy K Guha. 


VasalgelTM is a long-acting, nonhormonal contraceptive with a significant advantage over vasectomy: it is likely to be more reversible. The procedure is similar to a no-scalpel vasectomy, except a gel is injected into the vas deferens (the tube the sperm swim through), rather than cutting the vas (as is done in vasectomy). If a man wishes to restore flow of sperm, whether after months or years, the polymer is flushed out of the vas with another injection. https://www.medscape.com/viewarticle/775627


 EP055  is a small organic compound electrically hyper-polarizes a sperm cell membrane, disabling the sperm’s normal functions. 


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Avoid this, right?